For Oncology Nurses: Oral Selective Estrogen Receptor Degraders in Breast Cancer — Proceedings from the 2026 Annual ONS Congress

Posted on 08/18/2026
01:27:50 |

Featuring perspectives from Ms Blanca Ledezma, Dr Marissa Marti-Smith, Dr Heather McArthur and Dr Ruth M O'Regan, moderated by Dr McArthur, including the following topics:

· Introduction (0:00)

· Current Clinical Role of Oral Selective Estrogen Receptor Degraders (SERDs) in HR-Positive Metastatic Breast Cancer (3:37)

· Practical Considerations with Oral SERDs (15:43)

· Potential Role of Combination Approaches with Oral SERDs (26:33)

· Gastrointestinal Adverse Events Documented with Oral SERDs (38:19)

· Potential Role of Early Therapeutic Switching After Detection of an Emergent ESR1 Mutation (46:54)

· Other Class-Effect Toxicities Associated with Oral SERDs (1:00:56)

· Emerging Utility of Adjuvant Oral SERDs (1:10:20)

· Unique Toxicities Associated with 1 or More Oral SERDs (1:19:22)

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